Objective To investigate the effect of simple periodontal therapy and periodontal orthodontic treatment on periodontal disease. Methods? A total of 60 patients with periodontal disease admitted to Phoenix Branch of Zhangjiagang Traditional Chinese Medicine Hospital from June 2017 to June 2020 were selected as the research objects，and were divided into control group and observation group by random lottery，with 30 patients in each group.The control group was treated with simple periodontal treatment，and the observation group was treated with combined periodontal orthodontic treatment. The periodontal index，alveolar bone mineral density，crown length and root length were compared between the two groups. Results? After treatment，the gingival index（GI），attachment loss（CAL），gingival bleeding index（SBI），plaque index（PLI）and periodontal probing depth（PD）values of the observation group were lower than those before treatment and the control group（P＜0.05）；after treatment， the density of alveolar crest and apical area of the observation group were lower than those before treatment，and the observation group was lower than that of the control group（P＜0.05）；after treatment，the density of the observation group was lower than that of the control group（P＜0.05）The crown length was longer than that before treatment，and the observation group was longer than that of the control group（P＜0.05）；there was no significant difference in the root length between the two groups before and after treatment（P＞0.05）. Conclusion? For patients with periodontal disease，simple periodontal treatment and combined periodontal orthodontic treatment can play a therapeutic effect，but the latter can improve periodontal function，reduce alveolar bone density，increase crown length，but not increase the length of root，clinical use value is more significant.