Objective To explore the therapeutic effect of modified benign phacoemulsification in the treatment of patients with high myopia and cataract. Methods? A total of 50 patients with high myopia and cataract who were admitted to Rugao People's Hospital from January 2017 to May 2020 were selected as the study subjects. According to the different surgical treatment methods，they were divided into two groups，the conventional group and the modified group，with 25 patients in each group. Patients in the conventional group were given traditional intrahospital phacoemulsification surgery，while patients in the modified group were given improved surgical methods in the conventional group. The corneal endothelial cell count，complication rate and patient satisfaction were compared between the two groups before and after surgery. Results? Before surgery，the number of cornea endothelial cells in the modified group was（2 798.96±411.83）mm2，while that in the conventional group was（2 799.34±411.14）mm2，the difference was not statistically significant（P＞0.05）. However，at 1 week and 3 months after surgery，thenumber of cornea endothelial cells in the modified group was（2 797.25±411.11）mm2 and（2 698.21±411.26）mm2，and that in the conventional group was（2 632.21±448.50）mm2 and（2 025.51±513.52）mm2，respectively. There weresignificant differences between the modified group and the conventional group（P＜0.05）. The complication rate of the modified group was 4.00%，while that of the conventional group was 16.00%，with statistically significant difference（P ＜0.05）. The overall satisfaction was 92.00% in the modified group and 84.00% in the conventional group（P ＜0.05）.Conclusion? The modified benign phacoemulsification for patients with high myopia combined with cataract has a good clinical effect，can effectively maintain the stable state of corneal endothelial cell count， reduce the incidence of complications，and improve patient satisfaction，which is worthy of further promotion.