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空勤人员高尿酸血症危险因素研究
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R589

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Study on risk factors of hyperuricemia in aircrew
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    摘要:

    目的?分析空勤人员高尿酸血症(HUA)的相关影响因素,为体检鉴定和健康管理提供参考。方法?回顾性分析 2017 年 1 月至 2020 年 12 月某中心 7 685 名空勤人员体检者的临床资料,根据是否患 HUA 分为 HUA 组(1 612 例)和 无 HUA 组(6 073 例),比较两组空勤人员的基础资料 [ 性别、年龄、体质量指数(BMI)、高血压史、脂肪肝史、高胆 固醇血症史、吸烟史 ] 和实验室指标 [ 三酰甘油(TG)、空腹血糖(FBG)];以受试者工作曲线(ROC)分析 BMI、TG 预测空勤人员患 HUA 的价值;采用非条件 Logistic 逐步回归分析空勤人员 HUA 的危险因素。结果?HUA 组研究对象 中男性、有脂肪肝史、有高血压史、有高胆固醇血症史的占比显著高于无 HUA 组,HUA 组研究对象的 BMI、TG 水平显 著高于无 HUA 组(P <0.05);ROC 分析结果显示,BMI≥ 20.95?kg/m2 、TG≥ 1.55?mmol/L 是预测空勤人员患 HUA 的最佳截断值(P <0.05);非条件 Logistic 逐步回归分析显示,男性、有高血压史、有脂肪肝史、有高胆固醇血症史、 BMI≥ 20.95?kg/m2 、TG≥ 1.55?mmol/L 是空勤人员患 HUA 的独立危险因素(P <0.05)。结论?有脂肪肝史、男性、 有高血压史、有高胆固醇血症史、BMI≥ 20.95?kg/m2 、TG≥ 1.55?mmol/L 是空勤人员患 HUA 的独立危险因素,临床应 引起重视。

    Abstract:

    Objective?To explore the influencing factors of hyperuricemia (HUA) in aircrew,and provide reference for physical medical evaluation and health management. Methods?The clinical data of 7 685 cases of a Center from January 2017 to December 2020 were retrospectively analyzed, and they were divided into HUA group (1 612 cases) and non-HUA group (6 073 cases) according to whether they had HUA. The basic information of two sets of aircrew [gender, age, body mass index (BMI), history of hypertension, history of fatty liver, history of hypercholesterolemia and history of smoking] and laboratory index [triglyceride (TG), fasting blood glucose (FBG)] were collected and compared. ROC curve was used to analyze the value of BMI and TG in predicting HUA in aircrew. The risk factors of HUA in aircrew were determined by stepwise Logistic regression analysis. Results?The proportion of male, history of fatty liver, history of hypertension and history of hypercholesterolemia in HUA group was significantly higher than that in non-HUA group, and BMI and TG levels in HUA group were significantly higher than those in non-HUA group, with statistical significance (P < 0.05). According to ROC analysis, BMI ≥ 20.95 kg/m2 and TG ≥ 1.55 mmol/L were the best cut-off values for predicting HUA in aircrew with (P <0.05). Logistic stepstep regression analysis showed that history of hypertension, male, history of fatty liver, history of hypercholesterolemia, BMI≥ 20.95 kg/m2 , TG≥ 1.55 mmol/L were the risk factors for HUA in aircrew (P <0.05). Conclusion?History of fatty liver, male, history of hypertension, history of hypercholesterolemia, BMI≥ 20.95 kg/m2 , TG≥ 1.55 mmol/L are the risk factors for HUA in aircrew.

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  • 在线发布日期: 2022-08-08
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