Objective To analyze the influencing factors of shunt-dependent hydrocephalus (SDH) after interventional embolization of aneurysmal subarachnoid hemorrhage, and to provide clinical evidence experience and for reducing the incidence of shunt-dependent hydrocephalus and improving prognosis. Methods A total of 104 patients with aneurysmal subarachnoid hemorrhage who underwent cerebrospinal fluid drainage were selected from the Xiaolan Hospital Affiliated to Southern Medical University during January 2014 to December 2019. All patients were divided into 2 groups according to the criteria of "concurrent SDH or not", namely the SDH group (with SDH, a total of 15 cases) and the non-SDH group (without SDH, a total of 89 cases), and univariate analysis on the relevant clinical data of the two groups was done. The results with significant differences were included in the multivariate Logistic regression analysis which to explore the risk factors of concurrent SDH. Results Univariate analysis showed that preoperative Fisher classification, preoperative intraventricular hemorrhage, preoperative Hunt-Hess classification, preoperative rebleeding, postoperative intracranial infection, cerebrospinal fluid extraventricular drainage for treating acute hydrocephalus were significant differenes between the SDH group and non-SDH group (all P＜0.05). The results of multivariate Logistic regression analysis showed that intraventricular hemorrhage (OR=2.738, 95% CI: 1.249~5.803), Hunt-Hess grade Ⅲ~Ⅴ (OR=6.034, 95% CI: 3.243~28.663), rebleeding (OR=7.582, 95% CI: 4.503~49.431), and the mode of cerebrospinal fluid drainage in acute hydrocephalus (OR=3.828, 95% CI: 3.198~13.697) were the risk factors the occurrence of SDH (P＜0.05). Conclusion SDH is a common serious complication after interventional embolization for aneurysmal subarachnoid hemorrhage, and its risk factors include hemoventricular hemorrhage, Hunt-Hess classification, rebleeding, and CSF drainage for acute hydrocephalus. Clinically, patients should be evaluated for high-risk factors of hydrocephalus, and measures should be taken to prevent the occurrence of hydrocephalus.